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Dansyl Polymyxin B (DSL-PMB) is a fluorescent derivative of Polymyxin B. Its mode of action is in accordance to Polymyxin B activity. However MIC assays comparing DSL-PMB and parent Polymyxin B showed two to three-fold decrease in bacterial activity.1 2Polymyxin B is a cationic lipopeptide antibiotic which binds specifically to gram negative bacteria.3-6 It interacts with anionic lipopolysaccharide (LPS) molecules which are located in gram negative bacterial outer membrane.7 This interaction interferes with the outer membrane normal function causing leakage and enhanced uptake of the antibiotic.7 Resemblance in properties between Polymyxin B and DSL-PMB allows to fluorescently label gram negative bacteria and examine intracellular localization and penetration of Polymyxins in gram negative bacteria.2 8
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
SealMate Adhesive Sealing Film system features a unique method of applying sealing film on plates. SealMate provides fast, efficient and reliable seal on a plate without contamination. Film is available in roll format and reduces waste since it is supplied without protective backing or liner. Dispenser also functions as sealing paddle.
Each kit is supplied with 2 rolls of film. AeraSeal breathable sealing film is ideal for cell culture applications. Pierceable film fits culture plates or 96 well assay plates. Film is stable at -20° to +80°C. Roll contains film to cover 50 plates.
AeraSeal SealMate is a Trademark for Excel Scientific, Inc.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More